Top 11 dystonic reaction treatment in 2022

Below are the best information and knowledge on the subject dystonic reaction treatment compiled and compiled by our own team alltopus:

1. Dystonic Reactions

Author: www.ncbi.nlm.nih.gov

Date Submitted: 08/17/2021 10:04 AM

Average star voting: 3 ⭐ ( 66116 reviews)

Summary: An acute dystonic reaction is characterized by involuntary contractions of muscles of the extremities, face, neck, abdomen, pelvis, or larynx in either sustained or intermittent patterns that lead to abnormal movements or postures. The symptoms may be reversible or irreversible and can occur after taking any dopamine receptor-blocking agents. The etiology of acute dystonic reaction is thought to be due to dopaminergic-cholinergic imbalance in the basal ganglia. Reactions usually occur shortly after the initiation of an offending agent or an increased dose of a possible offending agent. Anticholinergic agents and benzodiazepines are the most commonly used agents to reverse or reduce symptoms in acute dystonic reaction. Acute dystonic reactions are often transient but can cause significant distress to the patient. Although rare, laryngeal dystonia can cause life-threatening airway obstruction.

Match with the search results: Treatment / Management

The most commonly available drugs in the emergency setting for the treatment of acute dystonic reactions are …. read more

Dystonic Reactions

2. The management of acute dystonic reactions

Author: www.nps.org.au

Date Submitted: 11/16/2020 11:34 PM

Average star voting: 4 ⭐ ( 81894 reviews)

Summary:

Match with the search results: Dystonia responds promptly to the anticholinergic benztropine 1-2 mg by slow intravenous injection. Most patients respond within 5 minutes and are symptom-free ……. read more

The management of acute dystonic reactions

3. How do I treat an acute dystonic reaction (ADR)? – SMI Adviser

Author: smiadviser.org

Date Submitted: 06/01/2021 02:35 PM

Average star voting: 4 ⭐ ( 33122 reviews)

Summary:

Match with the search results: In the emergency room or clinic, the parenteral administration of an anticholinergic (1 to 2 mg benztropine or 25-50 mg diphenhydramine) usually ……. read more

How do I treat an acute dystonic reaction (ADR)? - SMI Adviser

4. Medication-Induced Dystonic Reactions: Practice Essentials, Pathophysiology, Epidemiology

Author: emedicine.medscape.com

Date Submitted: 02/08/2020 07:37 PM

Average star voting: 3 ⭐ ( 93992 reviews)

Summary: Dystonic reactions are reversible extrapyramidal effects that can occur after administration of a neuroleptic drug. Symptoms may begin immediately or can be delayed hours to days.

Match with the search results: Medical treatment is usually effective to abate acute symptoms. With treatment, motor disturbances resolve within minutes, but they can reoccur ……. read more

Medication-Induced Dystonic Reactions: Practice Essentials, Pathophysiology, Epidemiology

5. Acute Dystonic Reaction in a 14-Year-Old Boy after Accidental Overuse of Nasal Metoclopramide

Author: emedicine.medscape.com

Date Submitted: 05/19/2019 09:27 AM

Average star voting: 5 ⭐ ( 49807 reviews)

Summary: We present the case of a 14-year-old boy who developed an acute dystonic reaction 5 h following the overuse of a nasal metoclopramide spray that his mother gave him thinking it was a nasal decongestan

Match with the search results: Dystonic reactions are reversible extrapyramidal effects that can occur after administration of a neuroleptic drug….. read more

Acute Dystonic Reaction in a 14-Year-Old Boy after Accidental Overuse of Nasal Metoclopramide

6. Stiff and Twisted

Author: www.karger.com

Date Submitted: 12/07/2020 11:21 PM

Average star voting: 5 ⭐ ( 98554 reviews)

Summary: Acute dystonic reactions are a distressing extrapyramidal side effect of antipsychotic and certain other medications.

Match with the search results: The management of an acute dystonic reaction caused by metoclopramide involves immediate discontinuation of the drug, and rapid administration of intravenous or ……. read more

Stiff and Twisted

7. Metoclopramide-induced acute dystonic reactions: a case report – Journal of Medical Case Reports

Author: litfl.com

Date Submitted: 06/16/2019 03:19 AM

Average star voting: 5 ⭐ ( 83643 reviews)

Summary: Acute dystonic reactions caused by drugs are uncommon in daily practice, whether in outpatient or in emergency settings. Such types of unfavorable reaction may cause the treating physician’s working diagnosis to be misled at a certain point. A 25-year-old Hindu female from Dharan with no previous medical history was being treated for acid peptic disease. Her local physician prescribed oral tablet metoclopramide 10 mg three times a day for 7 days and tablet pantoprazole 40 mg once daily for 7 days. After 24 hours of ingestion of 10 mg of tablet metoclopramide, she was admitted to our Koirala Institute of Health Sciences emergency department with sudden history of facial twitching, slurred speech, and abnormal tongue protrusion. Metoclopramide-induced acute dystonic reaction was diagnosed. After resuscitation, her symptoms reduced quickly, and she was successfully discharged home the same day. Early diagnosis would be aided by the use of clinical background along with focus on drug history usage, preventing life-threatening pitfalls. To decrease the acute dystonic reaction associated with metoclopramide use, higher frequency of prescription patterns should be taken into account.

Match with the search results: best used for acute dystonic reactions that are slow to resolve following benztropine administration — early use may lead to diagnostic confusion; Midazolam ……. read more

Metoclopramide-induced acute dystonic reactions: a case report - Journal of Medical Case Reports

8. Atypical Laryngeal Dystonia Caused by an Antiemetic

Author: wikem.org

Date Submitted: 01/16/2019 01:32 PM

Average star voting: 4 ⭐ ( 36038 reviews)

Summary:

Match with the search results: Diphenhydramine: 50-100mg over 2 minutes · Benztropine: 1-2mg in adults over 2 minutes · Biperiden · Trihexyphenidyl 2mg PO BID · IV > IM > PO ……. read more

Atypical Laryngeal Dystonia Caused by an Antiemetic

9. Metoclopramide induced acute dystonic reaction: a case report – BMC Research Notes

Author: psychopharmacologyinstitute.com

Date Submitted: 04/01/2021 11:12 PM

Average star voting: 5 ⭐ ( 44052 reviews)

Summary: Metoclopramide is a commonly used anti-emetic drug known to cause extrapyramidal symptoms as adverse effects, amongst which are dystonic reactions. These reactions are more frequent at high doses of metoclopramide, in female patients, children and adults less than 30 years of age. We hereby present the case of a 16 year old female who had dystonic reactions from metoclopramide, highlighting its unpredictable nature and the shortcomings of the management in resource-limited settings. A 16 year old female Muslim from the Extreme North of Cameroon with no significant past history, was treated for severe malaria and associated refractory vomiting using intravenous quinine and metoclopramide respectively. She developed dystonic reactions after being administered her second dose of metoclopramide. The drug was discontinued and she was administered 8 mg of chlorpheniramine by mouth. Her symptoms resolved after 4 h. She was discharged 2 days later with no further complaints. Metoclopramide causes dystonic reactions which are often unpredictable and is frequently prescribed by health providers. This creates an environment of anxiety for the patient and the caregiver, and can result in life threatening consequences. Patients on metoclopramide should be monitored closely to detect these reactions early, and health facilities should be equipped to cope with the adverse effects before administration.

Match with the search results: The drugs to use to address the acute dystonic reaction are the anticholinergics, benztropine or trihexyphenidyl or the antihistamine, ……. read more

Metoclopramide induced acute dystonic reaction: a case report - BMC Research Notes

10. RCEM Learning Dystonia Reference Material by Esther Wilson

Author: jmedicalcasereports.biomedcentral.com

Date Submitted: 06/04/2020 06:16 PM

Average star voting: 3 ⭐ ( 82255 reviews)

Summary: RCEM Learning Reference Acute dystonia is a movement disorder in which there is a state of abnormal tone produced by slow and sustained contractions

Match with the search results: Such types of unfavorable reaction may cause the treating physician’s working diagnosis to be misled at a certain point. Case presentation. A 25 ……. read more

RCEM Learning Dystonia Reference Material by Esther Wilson

11. Drug Induced Dystonia | Dystonia Medical Research Foundation Canada

Author: emed.ie

Date Submitted: 08/25/2020 07:29 PM

Average star voting: 4 ⭐ ( 32217 reviews)

Summary:

Match with the search results: Treatment / Management

The most commonly available drugs in the emergency setting for the treatment of acute dystonic reactions are …. read more

Drug Induced Dystonia | Dystonia Medical Research Foundation Canada

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