Top 22 morphea treatment in 2022

Author: www.mayoclinic.org

Date Submitted: 04/18/2021 12:43 PM

Average star voting: 3 ⭐ ( 95302 reviews)

Summary:

Match with the search results: . Oral medications. For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both….. read more

Author: emedicine.medscape.com

Date Submitted: 11/10/2019 02:02 PM

Average star voting: 5 ⭐ ( 78401 reviews)

Summary: Morphea, also known as localized scleroderma, is a disorder characterized by excessive collagen deposition leading to thickening of the dermis, subcutaneous tissues, or both. Morphea is classified into circumscribed, generalized, linear, and pansclerotic subtypes according to the clinical presentation and depth of tissue involvement.

Match with the search results: Successful treatment of severe and/or rapidly progressive morphea with systemic corticosteroids (eg, high-dose intravenous methylprednisolone in ……. read more

Author: www.uptodate.com

Date Submitted: 08/10/2020 05:00 PM

Average star voting: 5 ⭐ ( 95567 reviews)

Summary: A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Morphea

Match with the search results: There are multiple treatment options for active morphea; however, evidence in support of many of these therapies is limited….. read more

Author: rarediseases.info.nih.gov

Date Submitted: 09/28/2021 10:57 AM

Average star voting: 4 ⭐ ( 30105 reviews)

Summary: Morphoea, Localised scleroderma. Authoritative facts from DermNet New Zealand.

Match with the search results: Treatment for morphea is aimed at controlling the symptoms and depends on the severity and body surface area involved….. read more

Author: www.aocd.org

Date Submitted: 07/24/2019 09:11 AM

Average star voting: 3 ⭐ ( 78137 reviews)

Summary: Morphea is an autoimmune disease that causes sclerosis, or scarlike, changes to the skin.Autoimmune diseases occur when the immune system, which normally protec

Match with the search results: Fortunately it is generally self-limiting and if it is an easily hidden area may require no treatment at all. The usual treatments involve the use of high ……. read more

Author: dermnetnz.org

Date Submitted: 10/02/2020 09:49 AM

Average star voting: 3 ⭐ ( 45267 reviews)

Summary: A 66-year-old white woman with a history of hypertension and degenerative arthritis was seen in July 2003 by her primary care physician (PCP) for erythematous a

Match with the search results: There is no cure for morphoea. Treatment is aimed at halting ongoing disease activity and progression. Topical therapy. Topical therapy may help limited and ……. read more

Author: jamanetwork.com

Date Submitted: 08/24/2020 10:33 AM

Average star voting: 3 ⭐ ( 19105 reviews)

Summary: Morphea is a skin condition that involves a patch or patches of discolored or hardened skin on the face, neck, hands, torso, or feet.

Match with the search results: Generalized morphea, or morphea that involves the muscle and bone, is usually treated with phototherapy (regular exposure to UV light in a special machine) or a ……. read more

Author: jamanetwork.com

Date Submitted: 12/20/2019 03:25 AM

Average star voting: 5 ⭐ ( 79172 reviews)

Summary: Morphea is a rare skin condition that results in areas of skin becoming hardened or discolored. Learn more about the causes and prognosis here.

Match with the search results: Standard treatment for generalized morphea (GM) has included topical corticosteroids and lubrication, oral calcitriol, bath PUVA (psoralen–UV-A), UV-A1, ……. read more

Author: www.healthline.com

Date Submitted: 11/14/2021 04:00 AM

Average star voting: 3 ⭐ ( 80102 reviews)

Summary: Pansclerotic morphea (PSM) is a rare skin disease characterized by progressive stiffening of the skin with or without the typical superficial skin changes usually seen in morphea (localized scleroderma). Standard therapy, consisting of a combination of systemic glucocorticoids and methotrexate or mycophenolate mofetil, does rarely stop disease progression, which may lead to severe cutaneous sclerosis and secondary contractures. Little is known about the efficacy of newer biologicals such as abatacept, a fusion protein antibody against CTLA-4, or tocilizumab, a fully humanized IL-6R antibody, in the treatment of this pathology. We present the case of an 8 year old girl with an unusual, progressive stiffening of the skin, which was eventually diagnosed as pansclerotic morphea. A treatment with systemic glucocorticoids and methotrexate combined with tocilizumab led to a good clinical response within 2 months after initiation. In this paper, we discuss differential diagnoses to be considered and this new promising treatment option based on a case review of the literature.

Match with the search results: How is morphea treated? · applying sunscreen before going outside · avoiding harsh soaps and chemicals on your skin · using a humidifier to add moisture to the air ……. read more

Author: www.osmosis.org

Date Submitted: 12/02/2019 10:39 PM

Average star voting: 3 ⭐ ( 39593 reviews)

Summary: Morphea is a hardening of the skin. Cleaver Dermatology is here to help you with your concerns about this condition.

Match with the search results: Some treatment options for morphea treat only the outer layers of the skin. These include topical corticosteroids, used to reduce itching and inflammation ……. read more

Author: www.utsouthwestern.edu

Date Submitted: 10/27/2020 02:52 AM

Average star voting: 5 ⭐ ( 74539 reviews)

Summary: An overview of the two main categories of scleroderma.

Match with the search results: . Oral medications. For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both….. read more

Author: www.medicalnewstoday.com

Date Submitted: 09/18/2019 05:25 PM

Average star voting: 4 ⭐ ( 87205 reviews)

Summary: Morphea and systemic sclerosis are fibrosing disorders of the skin that share common inflammatory and immunologic pathways that are responsible for the vascular changes, increased collagen production, and extracellular matrix proliferation seen in both conditions. Recent advances in molecular biology techniques have furthered our knowledge of the potential underlying pathogenic mechanisms and offer new and provocative areas of research for novel diagnostic and therapeutic interventions. This review focuses on the role of vascular injury in the development of morphea, the use of ultrasonography as a diagnostic modality, and well-established and newly proposed treatments.

Match with the search results: Successful treatment of severe and/or rapidly progressive morphea with systemic corticosteroids (eg, high-dose intravenous methylprednisolone in ……. read more

Author: www.frontiersin.org

Date Submitted: 11/05/2019 03:34 AM

Average star voting: 4 ⭐ ( 90489 reviews)

Summary: Morphea: Evidence-based recommendations for treatment

Match with the search results: There are multiple treatment options for active morphea; however, evidence in support of many of these therapies is limited….. read more

Author: www.cleaverderm.com

Date Submitted: 10/12/2020 12:55 PM

Average star voting: 3 ⭐ ( 20969 reviews)

Summary: Morphea (localized scleroderma) is an autoimmune condition that causes hardening and thickening of the skin and sometimes symptoms like itching.

Match with the search results: Treatment for morphea is aimed at controlling the symptoms and depends on the severity and body surface area involved….. read more

Author: www.hopkinsmedicine.org

Date Submitted: 02/19/2019 04:41 PM

Average star voting: 4 ⭐ ( 18217 reviews)

Summary:

Match with the search results: Fortunately it is generally self-limiting and if it is an easily hidden area may require no treatment at all. The usual treatments involve the use of high ……. read more

Author: www.hindawi.com

Date Submitted: 03/19/2021 10:50 AM

Average star voting: 5 ⭐ ( 33747 reviews)

Summary: My wife has morphea spots on many areas of her body. We are currently treating them with Dovonex, which seems to help a little but is expensive. Do you have a better way to treat this disease? We have been told very little is known about how to treat it.

Match with the search results: There is no cure for morphoea. Treatment is aimed at halting ongoing disease activity and progression. Topical therapy. Topical therapy may help limited and ……. read more

Author: ijdvl.com

Date Submitted: 09/07/2019 04:32 PM

Average star voting: 3 ⭐ ( 72411 reviews)

Summary: Morphea: progress to date and the road ahead

Match with the search results: Generalized morphea, or morphea that involves the muscle and bone, is usually treated with phototherapy (regular exposure to UV light in a special machine) or a ……. read more

Author: www.verywellhealth.com

Date Submitted: 11/06/2021 04:30 PM

Average star voting: 5 ⭐ ( 83113 reviews)

Summary:

Match with the search results: Standard treatment for generalized morphea (GM) has included topical corticosteroids and lubrication, oral calcitriol, bath PUVA (psoralen–UV-A), UV-A1, ……. read more

Author: www.jaad.org

Date Submitted: 09/06/2019 05:10 AM

Average star voting: 5 ⭐ ( 47573 reviews)

Summary: A publicly available article also appearing in PubMed about Morphea

Match with the search results: How is morphea treated? · applying sunscreen before going outside · avoiding harsh soaps and chemicals on your skin · using a humidifier to add moisture to the air ……. read more

Author: www.health.harvard.edu

Date Submitted: 06/23/2021 01:47 PM

Average star voting: 3 ⭐ ( 66543 reviews)

Summary:

Match with the search results: Some treatment options for morphea treat only the outer layers of the skin. These include topical corticosteroids, used to reduce itching and inflammation ……. read more

Author: atm.amegroups.com

Date Submitted: 03/23/2020 07:31 AM

Average star voting: 4 ⭐ ( 60346 reviews)

Summary: Morphea, also known as localized scleroderma, is an uncommon idiopathic inflammatory disorder leading to the development of sclerotic plaques in the skin. The disorder preferentially affects females. The pathogenesis of morphea is not well-understood. The disorder is likely to have an autoimmune basis; environmental and genetic factors may also play a role in its etiology. Morphea has a variety of clinical presentations. Lesions of morphea typically begin as inflammatory plaques or patches that evolve into firm sclerotic lesions. Involvement may be limited to the dermis or may extend to underlying subcutaneous fat, muscle, or bone. The identification of characteristic clinical findings is often sufficient for the diagnosis of morphea. A biopsy can be a useful tool when the diagnosis is in question or to obtain information on the depth and intensity of the disease, and it should always extend at least into the subcutaneous fat. Morphea may cause joint contractures and other impairments secondary to tissue sclerosis and can be very debilitating cosmetically and functionally.

Match with the search results: . Oral medications. For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both….. read more

Author: www.rheumaderm-society.org

Date Submitted: 09/25/2021 07:52 AM

Average star voting: 5 ⭐ ( 81589 reviews)

Summary: Morphea often goes away without treatment, though it may leave scars or areas of discolored skin. You may want to pursue treatment if your symptoms persist

Match with the search results: Successful treatment of severe and/or rapidly progressive morphea with systemic corticosteroids (eg, high-dose intravenous methylprednisolone in ……. read more